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Rudolf Schröder (1),Olaf Häusler (2), Eugen Schwarz (3) and Klaus-Jürgen Steffens (1)
AAPS, 2001
(1): Universität Bonn, Pharmazeutische Technologie, 53121 Bonn, Germany
(2): Roquette Frères
(3): Meggle GmbH, 83512 Wasserburg, Germany
The study evaluates the influence of Mg-Stearate on the compaction and tablet behavior of co-spray dried compounds versus physical blends based on lactose and starch or lactose and MCC.
The change in physical properties by co-spray drying is reported for excipients. Also the influence of Mg-Stearate on the disintegration and dissolution.
The disintegration time depending on the concentration of Mg-Stearate is also featured.
For further information contact pharma.business.unit@roquette.com
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