>> Comparison of the Tableting Properties of a DC Lactose/Starch Compound versus a Physical Blend of DC Lactose and DC Starch

Download
full publication

(50) Ko

Philippe Lefèvre (1), Olaf Häusler (1), Eugen Schwarz (2)
AAPS, 2001
(1): Roquette Frères
(2): Meggle GmbH, 83512 Wasserburg, Germany

A new DC compound made of lactose and starch is now commercially available.

To evaluate the interest of such a product it has been compared to a physical blend of DC lactose and native starch.

Considering the fact that native starch is not well adapted to the direct compression, comparative trials of the compound versus a blend of other DC excipients (spray dried lactose and partially pregelatinized starch) were done.

Roquette Pharma is a global manufacturer and supplier of pharmaceutical excipients, actives and cosmetics ingredients, providing also services and formulation assistance. Roquette's pharma specialities are ideally suited for pharmaceutical and drug formulations : oral dosage forms such as tablets, capsules, paste products including tooth paste, injectable solutions, clinical nutrition and nutraceutical products, liquid and confectionery forms.