|
Olaf Häusler, PhD
Reproduced courtesy of Pharmaceutical Formulation & Quality magazine
A combination of starch and lactose is common and frequently used as an excipient for producing tablets. Lactose is a typical tablet binder, starch acts as an efficient disintegrant. Combining these two excipients requires an expensive wet granulation step to avoid problems of poor flow and a tendency of segregation.
Together, two European producers of pharmaceutical excipients, Meggle GmbH and Roquette Frères, have developed an innovative starch-lactose compound. This new excipient is commercially available under the brand name STARLAC®. STARLAC® meets the requirements of direct compaction, allowing for the use of well-known native corn starch in place of an expensive super-disintegrant in direct-compressible formulations.
Author: Olaf Häusler is Technical Project and Development Senior Management at Roquette Frères, Lestrem, France.
For further information contact pharma.business.unit@roquette.com
|
